Nuchal Fold Thickening
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References:

1) Benacerraf B. The significance of the nuchal fold in the second trimester fetus. Prenat Diag
2002;22:798-801
[PDF]

2) Gray DL, Crane JP. Optimal Nuchal Skin-Fold Thresholds Based on Gestational Age for Prenatal
Detection of Down Syndrome. Am J Obstet Gynecol 1994:171(5)1282-1286
[PDF]

3) Smith-Bindsman R, Hosmer W, Feldstein VA. Second-Trimester Ultrasound to Detect Fetuses with
Down Syndrome. JAMA 2001;285(8):1044-1055
[PDF]

4) AIUM Practice Guideline for the Performance of Obstetric Ultrasound Examinations (2007) [PDF]

5) Benacerraf BR, Frigoletto FD. Soft tissue nuchal fold in the second-trimester fetus: standards for
normal measurements compared to those in Down syndrome. Am J Obstet Gynecol
1987;157(5):1146-1149
[PDF]

6) Benacerraf BR, Laboda LA, Frigoletto FD. Thickened Nuchal Fold in Fetuses Not at Risk for
Aneuploidy. Radiology 1992;184:239-242
[PDF]

7) Bromley N, Lieberman E, Shipp TD. The Genetic Sonogram: A Method of Risk Assessment for
Down Syndrome in the Second Trimester. J Ultrasound Med 2002;21:1087-1096
[PDF]

8) Benacerraf BR, Frigoletto FD, Cramer DW. Down Syndrome: Sonographic Sign for Diagnosis in
the Second-Trimester Fetus. Radiology 1987;163:811-813
[PDF]  

9) Grandjean H, Sarramon MF. Sonographic Measurement of Nuchal Skinfold Thickness for
Detection of Down Syndrome in the Second-Trimester Fetus: A Multicenter Prospective Study.
Obstet Gynecol 1995;85:103-106
[PDF]

10) Cho JY, Kim KW, Lee YH. Measurement of nuchal skin fold thickness in the second trimester:
influence of imaging angle and fetal presentation. Ultrasound Obstet Gynecol 2005;25:253-257
[PDF]

11) Ben-Ami M, Perlitz Y, Mukary M. Nuchal fold thickness at 14-16 weeks' gestation as measured by
transvaginal sonography. Ultrasound Obstet Gynecol 2002;19:60-61
[PDF]  

12) Olson G, Saade GR, Zlatnik M. The effect of fetal neck position on nuchal fold thickness. Am J
Obstet Gynecol 2000;183:995-997
[PDF]  

13) Crane JP, Gray DL. Sonographically Measured Nuchal Skinfold Thickness As a Screening Tool
for Down Syndrome: Results of a Prospective Clinical Trial. Obstet Gynecol 1991;77:533-536
[PDF]

14) Benacerraf BR. The Role of the Second Trimester Genetic Sonogram in Screening for Fetal
Down Syndrome. Semin Perinatol 2005;29:386-394
[PDF]  

15) Borrell A, Costa D, Martinez JM. Early midtrimester fetal nuchal thickness: Effectiveness as a
marker of Down syndrome. Am J Obstet Gynecol 1996;175:45-49
[PDF]  

16) Nyberg DA, Souter VL. Sonographic Markers of Fetal Trisomies: Second Trimester. J Ultrasound
Med 2001;20:655-674 [PDF]

17) Van den Hof MC, Wilson RD. Fetal Soft Markers in Obstetric Ultrasound. J Obstet Gynaecol Can
2005;27(6):592-612
[PDF]  

18) Smith-Bindman R, Chu P, Goldberg JD. Second trimester prenatal ultrasound for the detection of
pregnancies at increased risk of Down syndrome. Prenat Diagn 2007;27:535-544
[PDF]

19) Nyberg DA, Souter VL, El-Bastawissi A. Isolated Sonographic Markers for Detection of Fetal
Down Syndrome in the Second Trimester of Pregnancy. J Ultrasound Med 2001;20:1053-1063
[PDF]